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The following table lists possible deletions.
Each sequence below represents the context around the guide's target, with deleted nucleotides shown as "-".
Sequences are ranked by micro-homology score. This score is correlated to the likelihood of finding a particular deletion, as predicted by the method of Bae et al. 2014.
| mh- Score | Sequence | Effect |
|---|---|---|
| TTGCTGTGCTGGTACTCGGCGTTCCCGGTGGCGCAGTCTGGGGTGCAGCTCACCTCGATTTCTTCATAGAAATCCGATTC | (Wild-type sequence) | |
| 384 | GGTACTCGGCGTTCCCGGTGGCGCAG------------CTCACCTCGATTTCTTCATAGA | 12 bp deleted → no frameshift |
| 330 | GGTACTCGGCGTTCCCGGTG---------------CAGCTCACCTCGATTTCTTCATAGA | 15 bp deleted → no frameshift |
| 233 | GGTACTCGGCGTTCCCGGTGGCGCAGTCTG-----CAGCTCACCTCGATTTCTTCATAGA | 5 bp deleted → frameshift |
| 230 | GGTACTCGGCGTTCCCGGTGG-----------GTGCAGCTCACCTCGATTTCTTCATAGA | 11 bp deleted → frameshift |
| 219 | GGTACTCGGCGTTCCCGGTGG------------TGCAGCTCACCTCGATTTCTTCATAGA | 12 bp deleted → no frameshift |
| 211 | GGTACTCGGCGTTCCCGGTGGCGCAGT-------GCAGCTCACCTCGATTTCTTCATAGA | 7 bp deleted → frameshift |
| 198 | GGTACTCGGCGTTCCCGGTGGC--------------AGCTCACCTCGATTTCTTCATAGA | 14 bp deleted → frameshift |
| 198 | GGTACTCGGCGTTCCCGG--------------GTGCAGCTCACCTCGATTTCTTCATAGA | 14 bp deleted → frameshift |
| 188 | GGTACTCGGCGTTCCCGGTGGCGC---------------TCACCTCGATTTCTTCATAGA | 15 bp deleted → no frameshift |
| 173 | GGTACTCGGCGTTCCCGGTGGCGCAGTCT-----------CACCTCGATTTCTTCATAGA | 11 bp deleted → frameshift |
| 170 | GGTACTCGGCGTTCCCGGTGGC-----------------TCACCTCGATTTCTTCATAGA | 17 bp deleted → frameshift |
| 156 | GGTACTCGGCGTTCCCGGTGGCGCAGTC-------------ACCTCGATTTCTTCATAGA | 13 bp deleted → frameshift |
| 134 | GGTACTCGGCGTTCCCGGTGGCGCAGTCT----------------CGATTTCTTCATAGA | 16 bp deleted → frameshift |
| 128 | GGTACTCGGCGTTCCCGGTGGCGCA-----------------CCTCGATTTCTTCATAGA | 17 bp deleted → frameshift |
| 126 | GGTACTCGG-----------------------GTGCAGCTCACCTCGATTTCTTCATAGA | 23 bp deleted → frameshift |
| 122 | GGTACTCGGCGTTCCCGGTGGCGCAGTC------------------GATTTCTTCATAGA | 18 bp deleted → no frameshift |
| 120 | GGTACTCGGCGTTCCCGGTGGCGCAGTCT------------------------TCATAGA | 24 bp deleted → no frameshift |
| 120 | GGTACTCGGCGTTCCCGGTGGCG------------------------ATTTCTTCATAGA | 24 bp deleted → no frameshift |
| 120 | GGTACTCGG------------------------TGCAGCTCACCTCGATTTCTTCATAGA | 24 bp deleted → no frameshift |
| 109 | GGTACTCGGC--------------------------AGCTCACCTCGATTTCTTCATAGA | 26 bp deleted → frameshift |
| 106 | GGT-------------------------------GCAGCTCACCTCGATTTCTTCATAGA | 31 bp deleted → frameshift |
| 99 | GGTACTCGGCGT----------------------GCAGCTCACCTCGATTTCTTCATAGA | 22 bp deleted → frameshift |
| 99 | GGTACTCG---------------------------------------ATTTCTTCATAGA | 39 bp deleted → no frameshift |
| 98 | GGTACTCGGCGTTCCC----------------------------TCGATTTCTTCATAGA | 28 bp deleted → frameshift |
| 94 | GGTACTCGGCGTTCC-----------------------------TCGATTTCTTCATAGA | 29 bp deleted → frameshift |
| 94 | GGTACTCGGC-----------------------------TCACCTCGATTTCTTCATAGA | 29 bp deleted → frameshift |
| 91 | GGTACTC----------------------------------ACCTCGATTTCTTCATAGA | 34 bp deleted → frameshift |
| 89 | GGTACTCGGCGTTCCCG------------------------------ATTTCTTCATAGA | 30 bp deleted → no frameshift |
| 89 | GG------------------------------GTGCAGCTCACCTCGATTTCTTCATAGA | 30 bp deleted → no frameshift |
| 77 | GGTACTCGGCGTTCCCGGTGGCGCAGTC---------------------------ATAGA | 27 bp deleted → no frameshift |
| 77 | GGTACTCGGCGTTC---------------------------ACCTCGATTTCTTCATAGA | 27 bp deleted → no frameshift |
| 66 | GGTACTCGGCG------------------------------------ATTTCTTCATAGA | 36 bp deleted → no frameshift |
| 63 | GGTACTCGGCGTTCCCGGTGGCGCA-------------------------------TAGA | 31 bp deleted → frameshift |
| 60 | GGTACTCGGCGTTC--------------------------------GATTTCTTCATAGA | 32 bp deleted → frameshift |
| 60 | GGTACTCGGCGTTC--------------------------------------TTCATAGA | 38 bp deleted → frameshift |
| 57 | GGTACTCGGCGTTCCCGGTGGCGCAG---------------------------------A | 33 bp deleted → no frameshift |
| 51 | GGTACTCGGCGTTC-----------------------------------------ATAGA | 41 bp deleted → frameshift |
| 45 | GGTAC--------------------------------------CTCGATTTCTTCATAGA | 38 bp deleted → frameshift |
| 31 | GGTACTC---------------------------------------------TTCATAGA | 45 bp deleted → no frameshift |
| 31 | GGTACTCGGCGTT-------------------------------------TCTTCATAGA | 37 bp deleted → frameshift |
| 28 | GGTACT-----------------------------------------------TCATAGA | 47 bp deleted → frameshift |
| 27 | GGTACTC------------------------------------------------ATAGA | 48 bp deleted → no frameshift |
| 13 | GGTA------------------------------------------------------GA | 54 bp deleted → no frameshift |