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The following table lists possible deletions.
Each sequence below represents the context around the guide's target, with deleted nucleotides shown as "-".
Sequences are ranked by micro-homology score. This score is correlated to the likelihood of finding a particular deletion, as predicted by the method of Bae et al. 2014.
| mh- Score | Sequence | Effect |
|---|---|---|
| AGCTGTCATCCTCCTGCTGCAATCGTCATTACAGTACCGCTGGTGACGCCACTCGGCGAACGCAAGTGGATAAATAGAAA | (Wild-type sequence) | |
| 382 | CTCCTGCTGCAATCGTCATTACAGTACCGC---------CACTCGGCGAACGCAAGTGGA | 9 bp deleted → no frameshift |
| 219 | CTCCTGCTGCAATCGTCATTACAGTACC------------ACTCGGCGAACGCAAGTGGA | 12 bp deleted → no frameshift |
| 191 | CTCCTGCTGCAATCGTCATTACAGT---------GACGCCACTCGGCGAACGCAAGTGGA | 9 bp deleted → no frameshift |
| 190 | CTCCTGCTGCAATCGTCATTACAGTACCGC-----------------------AAGTGGA | 23 bp deleted → frameshift |
| 182 | CTCCTGCTGCAATCGTCATTACAGTAC----------GCCACTCGGCGAACGCAAGTGGA | 10 bp deleted → frameshift |
| 179 | CTCCTGCTGCAATCGTCATTACAGTACCG----------------GCGAACGCAAGTGGA | 16 bp deleted → frameshift |
| 170 | CTCCTGCTGCAATCGTCATTACAGTACCGC-----------------GAACGCAAGTGGA | 17 bp deleted → frameshift |
| 154 | CTCCTGCTGCAATCGTCATTACAGTACCG-------------------AACGCAAGTGGA | 19 bp deleted → frameshift |
| 141 | CTCCTGCTGCAATCGTCATTACAGTAC---------------TCGGCGAACGCAAGTGGA | 15 bp deleted → no frameshift |
| 141 | CTCCTGCTGCAATCGTCATTAC---------------GCCACTCGGCGAACGCAAGTGGA | 15 bp deleted → no frameshift |
| 126 | CTCCTGCTGCAATCG-----------------------CCACTCGGCGAACGCAAGTGGA | 23 bp deleted → frameshift |
| 122 | CTCCTGCTGCAATCGTCATTACA------------------CTCGGCGAACGCAAGTGGA | 18 bp deleted → no frameshift |
| 122 | CTCCTGCTGCAATCGT------------------GACGCCACTCGGCGAACGCAAGTGGA | 18 bp deleted → no frameshift |
| 111 | CTCCTGCTGCAATCG------------------------------GCGAACGCAAGTGGA | 30 bp deleted → no frameshift |
| 110 | CTCCTGCTGCAATCGTCATTAC--------------------TCGGCGAACGCAAGTGGA | 20 bp deleted → frameshift |
| 95 | CTCCTGCTGCAATCGTCA-----------------------CTCGGCGAACGCAAGTGGA | 23 bp deleted → frameshift |
| 95 | CTCCTGCTG-----------------------GTGACGCCACTCGGCGAACGCAAGTGGA | 23 bp deleted → frameshift |
| 94 | CTCCTGCTGC-----------------------------CACTCGGCGAACGCAAGTGGA | 29 bp deleted → frameshift |
| 90 | CTCCTGCTGCAATCGTCATTACAGTAC------------------------GCAAGTGGA | 24 bp deleted → no frameshift |
| 81 | CTCCTGCTG--------------------------ACGCCACTCGGCGAACGCAAGTGGA | 26 bp deleted → frameshift |
| 81 | CTCCTG--------------------------GTGACGCCACTCGGCGAACGCAAGTGGA | 26 bp deleted → frameshift |
| 80 | CTCCTGCTGCAATCGTCATTACAGT--------------------------------GGA | 32 bp deleted → frameshift |
| 80 | CTCCTGC--------------------------------CACTCGGCGAACGCAAGTGGA | 32 bp deleted → frameshift |
| 77 | CTCCTGCTGCAATCGTC---------------------------GGCGAACGCAAGTGGA | 27 bp deleted → no frameshift |
| 76 | CTCCTGCTGCAATCG---------------------------------AACGCAAGTGGA | 33 bp deleted → no frameshift |
| 70 | CTCCTGCTGCAATCGTCATTAC-----------------------------GCAAGTGGA | 29 bp deleted → frameshift |
| 70 | CTCCTG-----------------------------ACGCCACTCGGCGAACGCAAGTGGA | 29 bp deleted → frameshift |
| 69 | CTCCTGCTGCAA-------------------------------------------GTGGA | 43 bp deleted → frameshift |
| 66 | CTCCTGCTGCA------------------------------CTCGGCGAACGCAAGTGGA | 30 bp deleted → no frameshift |
| 66 | CTCC------------------------------------ACTCGGCGAACGCAAGTGGA | 36 bp deleted → no frameshift |
| 64 | CTC-----------------------------------------GGCGAACGCAAGTGGA | 41 bp deleted → frameshift |
| 63 | CTCCTGCTGCAATCGTCATTACA-------------------------------AGTGGA | 31 bp deleted → frameshift |
| 62 | CTCCTGCTGCAATCG-------------------------------------CAAGTGGA | 37 bp deleted → frameshift |
| 62 | CTCCTGCTGC-------------------------------------GAACGCAAGTGGA | 37 bp deleted → frameshift |
| 54 | CTCCTGC----------------------------------------GAACGCAAGTGGA | 40 bp deleted → frameshift |
| 52 | CTCCTGCT-----------------------------------CGGCGAACGCAAGTGGA | 35 bp deleted → frameshift |
| 49 | CTCCTGCTGCAATCGTCA------------------------------------AGTGGA | 36 bp deleted → no frameshift |
| 45 | CTCCT--------------------------------------CGGCGAACGCAAGTGGA | 38 bp deleted → frameshift |
| 40 | CTCCTGC----------------------------------------------AAGTGGA | 46 bp deleted → frameshift |
| 38 | CTCCTGCTGCAATCGT-----------------------------------------GGA | 41 bp deleted → frameshift |
| 30 | CTCCTGCTGCAA--------------------------------------CGCAAGTGGA | 38 bp deleted → frameshift |
| 25 | CTCCTGCTG-------------------------------------------------GA | 49 bp deleted → frameshift |
| 22 | CTCCTG----------------------------------------------------GA | 52 bp deleted → frameshift |