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The following table lists possible deletions.
Each sequence below represents the context around the guide's target, with deleted nucleotides shown as "-".
Sequences are ranked by micro-homology score. This score is correlated to the likelihood of finding a particular deletion, as predicted by the method of Bae et al. 2014.
| mh- Score | Sequence | Effect |
|---|---|---|
| CCGGGTAGCCCCAGCGCCGTGTCGACGGCGACCGCGGAGATGGCAGTGGGGAGCTAGGGTCACCTTGTGATGCGAGCGCT | (Wild-type sequence) | |
| 347 | CCAGCGCCGTGTCGACGGCGACCGCGGAG--------------CTAGGGTCACCTTGTGA | 14 bp deleted → frameshift |
| 296 | CCAGCGCCGTGTCGACGGCGACCGCGG------CAGTGGGGAGCTAGGGTCACCTTGTGA | 6 bp deleted → no frameshift |
| 283 | CCAGCGCCGTGTCGACGGC---------------AGTGGGGAGCTAGGGTCACCTTGTGA | 15 bp deleted → no frameshift |
| 255 | CCAGCGCCGTGTCGACGGCGACCGC---------AGTGGGGAGCTAGGGTCACCTTGTGA | 9 bp deleted → no frameshift |
| 219 | CCAGCGCCGTGTCGACGGCGACCGCGG------------GGAGCTAGGGTCACCTTGTGA | 12 bp deleted → no frameshift |
| 211 | CCAGCGCCGTGTCGACGGCGACCGCGGAG-------TGGGGAGCTAGGGTCACCTTGTGA | 7 bp deleted → frameshift |
| 208 | CCAGCGCCGTGTCGACGGCGACCGCGG-------------GAGCTAGGGTCACCTTGTGA | 13 bp deleted → frameshift |
| 164 | CCAGCGCCGTGTCGACGGCGACCGCGGAGA------------GCTAGGGTCACCTTGTGA | 12 bp deleted → no frameshift |
| 154 | CCAGCGCCGTGTCGACGGCGACCGC-------------------TAGGGTCACCTTGTGA | 19 bp deleted → frameshift |
| 140 | CCAGCGCCGTGTCGACGGCGACCGCGG---------------------GTCACCTTGTGA | 21 bp deleted → no frameshift |
| 140 | CCAGCGCCGTGTCGACGG---------------------GGAGCTAGGGTCACCTTGTGA | 21 bp deleted → no frameshift |
| 133 | CCAGCGCCGTGTCGACGGCGACCGCGG----------------------TCACCTTGTGA | 22 bp deleted → frameshift |
| 133 | CCAGCGCCGTGTCGACGG----------------------GAGCTAGGGTCACCTTGTGA | 22 bp deleted → frameshift |
| 129 | CCAGCGCCGTG---------------------------GGGAGCTAGGGTCACCTTGTGA | 27 bp deleted → no frameshift |
| 126 | CCAGCGCCGTGTCGACGG-----------------------AGCTAGGGTCACCTTGTGA | 23 bp deleted → frameshift |
| 122 | CCAGCGCCGTGTCGACGGCGACCGCGGAG------------------GGTCACCTTGTGA | 18 bp deleted → no frameshift |
| 114 | CCAGCGCCGTGTCGACGGC-------------------------TAGGGTCACCTTGTGA | 25 bp deleted → frameshift |
| 106 | CCAGCGCCGTGTCGACGGCGACC-------------------------------TTGTGA | 31 bp deleted → frameshift |
| 105 | CCAGCGCCGTGTCGACGGCGA---------------------GCTAGGGTCACCTTGTGA | 21 bp deleted → no frameshift |
| 105 | CCAGCGCCGTG---------------------GCAGTGGGGAGCTAGGGTCACCTTGTGA | 21 bp deleted → no frameshift |
| 103 | CCAGCGC---------------------------AGTGGGGAGCTAGGGTCACCTTGTGA | 27 bp deleted → no frameshift |
| 101 | CCAG--------------------------------TGGGGAGCTAGGGTCACCTTGTGA | 32 bp deleted → frameshift |
| 94 | CCAGC-----------------------------AGTGGGGAGCTAGGGTCACCTTGTGA | 29 bp deleted → frameshift |
| 89 | CCAGCGCCGTGTCGACGG------------------------------GTCACCTTGTGA | 30 bp deleted → no frameshift |
| 86 | CCAGCGCCGTGT-------------------------GGGGAGCTAGGGTCACCTTGTGA | 25 bp deleted → frameshift |
| 84 | CCAGCGCCGTGTCGACGG-------------------------------TCACCTTGTGA | 31 bp deleted → frameshift |
| 77 | CCAGCGCCGTGTCGA---------------------------GCTAGGGTCACCTTGTGA | 27 bp deleted → no frameshift |
| 75 | CCAGCGCCGTGTC--------------------------------------ACCTTGTGA | 38 bp deleted → frameshift |
| 71 | CCAGC---------------------------------------TAGGGTCACCTTGTGA | 39 bp deleted → no frameshift |
| 66 | CCAGCGCCGTGTCGACGGCGACCGCGGAGA------------------------------ | 30 bp deleted → no frameshift |
| 62 | CCAGCGC-------------------------------------TAGGGTCACCTTGTGA | 37 bp deleted → frameshift |
| 60 | CCAGCGCCGTGTCGACGGCGACCGCGGA-------------------------------- | 32 bp deleted → frameshift |
| 47 | CCAGCGCCGTGTCGAC-------------------------------------CTTGTGA | 37 bp deleted → frameshift |
| 45 | CCAGCGCCGTG------------------------------------------------A | 48 bp deleted → no frameshift |
| 42 | CCAGCGCCGTGTCGACGGCGA--------------------------------------- | 39 bp deleted → no frameshift |
| 40 | CCAGCGCCGT----------------------------------------CACCTTGTGA | 40 bp deleted → frameshift |
| 40 | CCAGCGCCGTGT----------------------------------------------GA | 46 bp deleted → frameshift |
| 40 | CCAGCGCC----------------------------------------------TTGTGA | 46 bp deleted → frameshift |
| 34 | CCAG-------------------------------------------GGTCACCTTGTGA | 43 bp deleted → frameshift |
| 31 | CCAGCGCCGTGTCGA--------------------------------------------- | 45 bp deleted → no frameshift |
| 29 | CC----------------------------------------------------TTGTGA | 52 bp deleted → frameshift |
| 25 | CCA-------------------------------------------------CCTTGTGA | 49 bp deleted → frameshift |